The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura
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منابع مشابه
The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura
BACKGROUND The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease. Migraine, with and without aura (MA and MO), is a prevalent and complex neurovascular disorder that may also be affected by genetically influenced hyperhomocysteinaemia. To determine whether the C677T...
متن کاملThe methylenetetrahydofolate reductase gene variant C677T influences susceptibility to migraine with aura
Background: The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease. Migraine, with and without aura (MA and MO), is a prevalent and complex neurovascular disorder that may also be affected by genetically influenced hyperhomocysteinaemia. To determine whether the C677...
متن کاملMethylenetetrahydrofolate Reductase Gene Variant (MTHFR C677T) and Migraine: A Case Control Study and Meta-analysis
BACKGROUND Migraine is a common disorder that often coexists with depression. While a functional polymorphism in methyleneterahydrofolate reductase gene (MTHFR C677T) has been implicated in depression; the evidence to support an association of MTHFR with migraine has been inconclusive. We aim to investigate the effect of this variant on propensity for migraine and to perform a systematic review...
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Introduction: One factor known to cause thrombophilia in women with unexplained recurrent spontaneous abortion (RSA) is C677T polymorphism of methylenetetrahydrofolate reductase gene. This study aimed to determine the association between RSA and MTHFR C677T polymorphism in Iranian patients. Methods: In this case-control study, 30 patients with previous history of two or more consecutive unexpla...
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Esophageal cancer (EC) is a global health problem, and an estimated 482,300 new esophageal cancer cases and 406,800 deaths occurred in 2008 worldwide (Jemal et al., 2011). Its incidence rates vary internationally, and the highest rates found in Southern and Eastern Africa and Eastern Asia were nearly 16-fold, compared with lowest rates observed in Western and Middle Africa and Central America i...
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ژورنال
عنوان ژورنال: BMC Medicine
سال: 2004
ISSN: 1741-7015
DOI: 10.1186/1741-7015-2-3